Preheat oven to 350°F. Grease a 9x5-inch loaf pan.
In a large bowl, whisk together the flour, baking powder, salt, garlic powder, and onion powder.
In a separate bowl, mix together the melted butter, cheddar cheese, milk, and eggs.
Add the wet ingredients to the dry ingredients and mix until just combined.
Pour the batter into the prepared loaf pan and bake for 45 minutes, or until a toothpick inserted into the center comes out clean.
Let cool for 10 minutes before slicing and serving. Enjoy!